Amino Acids Deficiency: Causes, Symptoms, and Disorders

AminoAcidProducts | November 27, 2019 | Health

Amino acid deficiency is caused by a lack of amino acids in the body. These amino acids are an essential component which the body uses to perform several integral functions. There are about twenty-two amino acids and each of these amino acids plays a specific role in the body. Some of these amino acids are produced within our body but there are others known as essential amino acids that our body cannot produce. We get these essential amino acids from food sources. This is one of the reasons why we are encouraged to eat a balanced diet.

Amino Acids Deficiency

When we eat protein-rich food, our digestive system acts on this protein, breaking it down to become amino acids. Our body then acts on these amino acids, combining them in different ways to perform various bodily functions. If these amino acids are absent then these functions can not be carried out thus leading to deficiencies. There are several symptoms that are associated with each unique deficiency and the accompanying disorders. We will be looking at them here.

Metabolic Disorders

The most common cause of amino acid deficiency is metabolic disorders. Our body undergoes a metabolic process by breaking down food into different nutrients and disperses it via the blood to the places where they are needed. The body of a person who has a metabolic disorder will not be able to carry out this process. There are people whose bodies are not able to process carbohydrates, some cannot process fats, proteins, vitamins or any of the classes of food.

Our focus here is on the metabolic disorder that comes from the body’s inability to break down protein into amino acid thus leading to a deficiency or lack of amino acids. This condition is known as amino acid metabolism disorders. There are different types of this disorder, it includes; maple syrup urine disease, phenylketonuria (PKU), methylmalonic aciduria, and Homocystinuria.

1. Maple syrup disease

This disorder is inherited. It is caused by the body’s inability to properly process amino acids. The name of this condition is gotten from the sweet odor of an infant’s urine, which is an infant who is affected with this condition. The symptoms of this disorder include poor feeding, abnormal movements, vomiting, delayed development, and lethargy.

If this condition is left untreated it can result in coma, seizures, and death. This disease is usually classified by the pattern of symptoms and signs noticed. The most severe and common form of maple syrup urine disease becomes obvious immediately after childbirth. It is known as the classic type. There are other types that are obvious during childhood or late infancy. These types are usually milder but still result in health issues and delayed development if left untreated.

2. Phenylketonuria

This is usually referred to as PKU. It is also an inherited condition. It causes the blood level of phenylalanine to increase. Phenylalanine is an amino acid obtained from our diet, it is an essential amino acid. If this condition is left untreated, the level of phenylalanine will increase to an extent where it becomes harmful to the body. This can lead to critical health problems such as intellectual disability.

The symptoms of phenylketonuria differ based on the intensity of the condition. Classic PKU is the most severe type of this condition. Infants who suffer from this condition do not show signs instantly until a few months later. If these children are not treated they will develop a lifelong intellectual disability. Other common symptoms include delayed development, seizures, psychiatric disorders, and behavioral problems.

The skin and hair of the affected children take on a lighter tone than the other members of the family who are unaffected. They might also develop eczema and skin disorders. The variant type of this condition has a lesser risk of developing brain damage and the milder form of phenylketonuria may not need treatment. Women suffering from PKU are at high risk of losing their pregnancy.

3. Methylmalonic acidemia

This amino acid deficiency is an inherited condition caused by the body’s inability to break down proteins. This leads to a build-up of methylmalonic acid. It is a rare condition and is usually diagnosed during the first twelve months of life. A child gets this condition by inheriting a defective gene from both mother and father.

Most of the time the newborn dies even before the condition is diagnosed. There are several symptoms of this condition which usually comes up as soon as the baby begins to consume food that contains proteins. This worsens the condition and can result in stroke and seizure. Some of the other symptoms include progressive encephalopathy, delayed development, lethargy, vomiting, seizures, yeast infections, actions, and dehydration.

The intensity of these symptoms can be reduced by eating food low in protein. The patients should avoid being around people with an infectious illness such as flu and cold. The diet of the child must be closely monitored and there are different supplements that can be taken, these supplements should contain carnitine and cobalamin.

4. Homocystinuria

This is caused by the absence of an amino acid called methionine in the body leading to the buildup of homocysteine. Normally homocystinuria is found in small quantities in the urine and blood but people with this condition have an elevated level.

The symptoms of this deficiency develop within the first few months of life. These symptoms include seizures, megaloblastic anemia, stunted growth, intellectual disability, movement problem, slender build, pale skin and hair, irregularly shaped chest, blood, clots, and weak bones.

This condition is caused by the mutation of certain genes and thus it can be passed down from parent to child. It is inherited. A treatment plan can be administered by the doctor but the child would generally have to stop eating food that has high protein content.

We have seen that most of these deficiencies are inherited. This is why expecting parents are usually advised to undergo a series of tests in order to ascertain if their unborn children are at risk of any amino acid deficiency.

Man standing mixing fresh salad with two wooden ladle

443 thoughts on “Amino Acids Deficiency: Causes, Symptoms, and Disorders

  1. Thanx for the effort, keep up the good work Great work, I am going to start a small Blog Engine course work using your site I hope you enjoy blogging with the popular you express are really awesome. Hope you will right some more posts.

  2. An interesting discussion is definitely worth comment.

    There’s no doubt that that you ought to publish more on this subject, it
    may not be a taboo matter but typically folks don’t talk about
    these subjects. To the next! Best wishes!!

  3. You’re so cool! I do not suppose I have read anything
    like that before. So nice to discover someone with some genuine thoughts on this issue.
    Really.. many thanks for starting this up. This site
    is one thing that’s needed on the internet, someone
    with some originality!

  4. Pingback: viagra 100mg
  5. Pingback: best cialis site
  6. Pingback:
  7. You really make it seem so easy together with your presentation but I to find this matter to be actually something that I believe I would by no means understand. It seems too complex and very broad for me. I’m having a look forward in your next submit, I¦ll try to get the cling of it!

  8. Hello! I realize this is sort of off-topic but I needed to ask. Does running a well-established blog such as yours take a lot of work? I am completely new to blogging but I do write in my diary on a daily basis. I’d like to start a blog so I will be able to share my own experience and thoughts online. Please let me know if you have any kind of suggestions or tips for brand new aspiring blog owners. Appreciate it!|

  9. I’m really enjoying the theme/design of your
    web site. Do you ever run into any web browser
    compatibility issues? A small number of my blog readers have complained about my blog
    not working correctly in Explorer but looks great in Firefox.
    Do you have any solutions to help fix this issue?

  10. Pingback: buy tylenol
  11. We stumbled over here different web address and thought I may as well check things out. I like what I see so i am just following you. Look forward to looking at your web page repeatedly.|

  12. Pingback: chloroquine otc
  13. Excellent weblog right here! Additionally your website quite a bit up fast!
    What web host are you the usage of? Can I am getting your affiliate hyperlink on your host?
    I want my web site loaded up as fast as yours lol

  14. I’m extremely inspired along with your writing abilities as neatly as with the structure on your weblog. Is that this a paid subject matter or did you customize it yourself? Anyway keep up the excellent quality writing, it’s uncommon to look a great blog like this one nowadays..|

  15. Fascinating blog! Is your theme custom made or did you download it from somewhere? A theme like yours with a few simple tweeks would really make my blog jump out. Please let me know where you got your design. Kudos|

  16. Hey There. I found your blog using msn. This is an extremely well written article. I’ll be sure to bookmark it and return to read more of your useful information. Thanks for the post. I will certainly comeback.|

  17. I don’t even know how I ended up here, but I thought this post was good. I don’t know who you are but definitely you are going to a famous blogger if you are not already 😉 Cheers!|

  18. you’re really a excellent webmaster. The website loading speed is incredible. It seems that you are doing any unique trick. Also, The contents are masterpiece. you have performed a great activity in this matter!|

  19. hello there and thank you for your information – I’ve certainly picked up anything new from right here. I did however expertise a few technical points using this website, as I experienced to reload the website lots of times previous to I could get it to load correctly. I had been wondering if your web host is OK? Not that I’m complaining, but slow loading instances times will sometimes affect your placement in google and can damage your high quality score if advertising and marketing with Adwords. Anyway I am adding this RSS to my e-mail and could look out for a lot more of your respective intriguing content. Make sure you update this again soon.|

  20. Its like you read my mind! You appear to know a lot about this, like you wrote the book in it or something. I think that you can do with a few pics to drive the message home a little bit, but instead of that, this is great blog. A fantastic read. I will definitely be back.|

  21. An interesting discussion is worth comment. I do believe that you ought to write more about this subject matter, it may not be a taboo matter but typically people don’t talk about these topics. To the next! All the best!!|

  22. Wow, fantastic blog layout! How long have you been blogging for? you made blogging look easy. The overall look of your site is magnificent, as well as the content!|

  23. Hi, I do think this is an excellent site. I stumbledupon it 😉 I will return yet again since i have book-marked it. Money and freedom is the best way to change, may you be rich and continue to guide other people.|

  24. Nota: Este grupo comprende la congelación rápida de peces, crustáceos, etc.; conservación mediante envasado y esterilización (en aceite, en escabeche, al natural, en salsas, incluso platos preparados cuyo principal componente sea el pescado); elaboración de salazones y escabeches; secado, ahumado, prensado, etc., de pescados, así como la preparación, conservación y envase de otros productos marinos y de agua dulce (caviar, huevos de esturión, ranas, salmónidos, algas, etc.).

Leave a Reply

Your email address will not be published. Required fields are marked *

Subscribe for our newsletter