What is Glutamine Synthetase?

AminoAcidProducts | June 26, 2019 | Health

What’s glutamine synthetase? This is an important enzyme the body needs for breaking down nitrogen. It does this by using the amino acid glutamic acid and the chemical compound ammonia. This helps to form the amino acid glutamine. It’s important to know what this enzyme is about and its job in helping the body to function properly. Enzymes themselves are found in all living organisms and help to cause some kind of chemical reaction. Fun Fact: human cells have about 1,300 different kinds of enzymes. When enzymes team up with coenzymes they make up almost 100,000 different chemicals that help the body to function properly.

Since glutamine synthetase’ job focuses on nitrogen it’s very important. We often talk about how chemicals like oxygen affect our bodies. However, we shouldn’t forget about others like nitrogen. Here’s why. Amino acids are the “building blocks” of protein and all of them contain nitrogen. So, it’s important for the body to turn the chemical into energy so it can use it for different functions that involve body parts like hair, skin, and muscles. It’s not really enough for our bodies to get certain chemicals, nutrients, etc. It’s then important for the body to turn this stuff into energy so it’s about to use them.

 

What Is Glutamine?

This is one of the body’s amino acids, which themselves are the building blocks of proteins. They’re found naturally in the body and have different functions. Glutamine is one of the “essential” amino acids so we have to get it from food since the body doesn’t produce it.

The body can get glutamine from various sources. For example, some food sources include:

  • Meat
  • Seafood
  • Eggs
  • Beans
  • Cabbage
  • Nuts
  • Dairy

So, if you want to boost your body’s levels of this amino acid these are some of the best options. You can also get the substance from dietary supplements. These are over-the-counter (OTC) products so you won’t need a prescription.

Let’s get back to glutamine. Studies show that this amino acid can provide some key benefits. They include the body’s immune system and digestive system. If you want better gut health then you should consider glutamine.

There’s some debate about the use of glutamine for other functions. It doesn’t seem to help much with strength/muscle gains based on studies.

It might help with muscle recovery but the results of studies are mixed so it’s unclear. You have more reliable options if you want supplements that have been proven to help build lean muscle mass or achieve strength gains.

You might have seen glutamine advertised as a “testosterone booster.” The problem is there isn’t much scientific evidence it can significantly boost the male hormone. It can increase levels by about one-third but you could get the same results from a good night’s sleep.

There are also some possible side-effects from taking glutamine. They include swelling, muscle/joint pain, and LBM. These symptoms aren’t too serious but users should still contact their doctor if they experience any.

As always you should tell your doctor about any OTC/Rx meds you’re taking now. This will help to prevent any negative reactions from taking the two substances.

 

What Is a Synthetase?

This is a type of enzyme that helps to connect two molecules. This is usually done by using extra energy from a particular process. It’s a very technical process but is important in terms of glutamine synthetase.

You’ve probably heard of enzymes before but most of us aren’t really sure what they’re about. Our bodies need them but how are enzymes different from stuff like vitamins and minerals? Chemical reactions are important for living organisms to stay alive.

This is why enzymes are so important. For example, even organisms that only have one cell can actually be involved in hundreds of different chemical reactions.

So just imagine how important this process is for humans. Humans have about 37 TRILLION cells in their bodies. This explains why enzymes are so important for how cells react with each other.

This even involves the process of synthetase as molecules connect with other molecules. This is why it’s important to make sure you’re getting enough enzymes in your diet. This will help everything to run smoother.

The good news is you don’t really have to worry about how enzymes work. If you eat a wide variety of healthy foods you can get them from different amino acids.

For example, different foods contain different amino acids. In addition, different amino acids have different enzymes. If you eat different foods that are high in glutamine then the enzymes you get from them will work effectively to connect molecules within your body.

Dietary supplements are another option. This is another way to boost your glutamine intake and make sure you’re getting the types and number of enzymes your body needs.

On the other hand, eating lots of empty calories will have the opposite effect. You could end up with an amino acid/enzyme deficiency. This is a situation you’ll want to avoid.

 

What Is Glutamine Synthetase?

These molecules check your body’s levels of amino acids that are high in nitrogen. It helps to determine when your body needs to make more.

The body’s cells are in an environment that’s always changing. This can even be affected by the food that we eat every day. Sometimes we eat healthy foods. Other days we eat high-carb or high-protein food. The food we eat alone can have a big effect on the body’s chemicals.

Glutamine synthetase is an enzyme that’s important for controlling how cells use nitrogen. The amino acid glutamine is used to build proteins and provides the chemical nitrogen to the body’s enzymes. They, in turn, build molecules that are nitrogen-rich.

So, it’s important for glutamine-building enzymes to be controlled carefully. It must be switched on when the body needs nitrogen so the cells get the nutrients they need. Then it should switch off when the body has enough nitrogen.

It’s helpful to think of this enzyme as a mini computer that watches how many nitrogen-full molecules the body has. When the body has too many molecules of certain amino acids the enzymes pick this up then slows down production a little.

Meanwhile, when the levels of amino acids increase, they should slow down the enzymes more. When the body has enough of the nitrogen the “computer” shuts down for the day.

This enzyme is very big. The human body’s cells also make different types of glutamine synthetase. In fact, sometimes it can be similar to enzymes of bacteria. They’re also controlled by groups of chemicals that are nitrogen-rich.

The brain also produces this type of enzyme. It’s used for sending signals between the brain and body. This version of the enzymes is constantly active. It’s easily one of the most important types of glutamine synthetase.

Glutamine synthetase is an enzyme that’s found in many tissues including the kidneys.

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